Table I.
Correlation between CDCA5 expression and clinicopathological characteristics of the HCC cases.
CDCA5 expression levels | ||||
---|---|---|---|---|
HCC clinical variables | Low (n=39) | High (n=59) | χ2 | P-value |
Sex | 1.234 | 0.266 | ||
Male | 32 | 53 | ||
Female | 7 | 6 | ||
Age (years) | 1.448 | 0.229 | ||
<50 | 10 | 22 | ||
≥50 | 29 | 37 | ||
Cirrhosis | 1.486 | 0.223 | ||
Absence | 21 | 39 | ||
Presence | 18 | 20 | ||
Metastasis | 1.274 | 0.391a | ||
Absence | 35 | 48 | ||
Presence | 4 | 11 | ||
Histological grade | 4.506 | 0.034b | ||
I–II | 30 | 33 | ||
III | 9 | 26 | ||
Maximal tumor size (cm) | 7.090 | 0.003b | ||
<5 | 23 | 17 | ||
≥5 | 16 | 42 | ||
Tumor number | 2.266 | 0.132 | ||
Single | 29 | 37 | ||
Multiple | 8 | 21 | ||
TNM stage | 5.320 | 0.019b | ||
I–II | 24 | 22 | ||
III–IV | 15 | 37 |
Statistical analysis was performed by Pearson's χ2 test.
Fisher's exact test.
Statistically significant difference. CDCA5, cell division cycle associated 5; HCC, hepatocellular carcinoma; TNM, tumor, node, metastasis.