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EVs play a role in recruiting SCs to an oncogenic phenotype. A, Secreted MMP-2 activity of SCs grown in CAsE-PE CM containing EVs or devoid of EVs for 3 weeks. Asterisk denotes statistical significance (one factor ANOVA, p = .02, n = 3). Post-hoc comparisons were made using Tukey’s HSD test. Bars ± SEM. B, Morphology of SCs grown in CAsE-PE CM for 3 weeks (scale bars = 200 µm).
