Figure 1.

The phosphorylation of HSF1 was reduced by both MI and hypoxic stimuli. A, Representative Western blots and (B) quantitative results of total and phosphorylation level of HSF1 in the LV border zone of MI 1 wk after LAD ligation. N = 5 per experimental group. MI, myocardial infarction. *P < .05 compared with sham. C, Representative Western blots and (D) quantitative results of total and phosphorylation level of HSF1 in NRCMs stimulated by hypoxia. N = 5 independent experiments. GAPDH was served as internal control. NO, normoxia. HO, hypoxia. All data are expressed as mean ± SEM *P < .05 compared with NO