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. 2018 Aug 21;9:1967. doi: 10.3389/fmicb.2018.01967

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Copyright © 2018 Ye, Lv, Wu, Li, Shi, Fang, Guo, Jiang, Yan, Ye and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Butyrate alleviated the microbiome dysbiosis induced by the MCD diet. (A,B) PCoA plot of the microbiota based on unweighted UniFrac metric (A) and weighted UniFrac metric (B). Each symbol represents one sample (N = 6 per group). (C–E) Top most abundant taxa at the phylum (C), family (D), and genus (E) level. (F) LEfSe cladogram representing taxon enriched in the MCD (red) and MCD + SoB group (green). Rings from the inside out represented taxonomic levels from phylum to genus levels. Sizes of circles indicate the relative abundance of the taxa. (G) Discriminative biomarkers with an LDA score > 4.8.