Figure 4.

Decreased plaque burden in the aortas of ApoE^−/− mice on HFD for 6 wk after Fgr and Lyn abolition. A, Plaque burden in the aortas of Apoe^−/− animals or ApoE^−/− mice deficient in Fgr or Lyn assessed using analysis of oil red O staining after 6 wk of HFD (n = 10‐12). B, False colour masks depicting plaque burden in the aortas of Apoe^−/− animals or ApoE^−/− mice deficient in Fgr or Lyn. C, Site specific analysis of plaque burden within the aorta (n = 10‐12). Data are mean ± SEM *P < .05, **P < .01 ApoE ^−/− Fgr ^−/− and ApoE ^−/− Lyn ^−/− mice compared to ApoE ^−/− using one‐way ANOVA followed by a Dunnett (A) or Bonferroni (B) post‐test