Figure 5.

Decreased size and number of plaques in the descending aorta of ApoE^−/− mice on HFD for 6 wk after Fgr and Lyn abolition. A, B, ApoE ^−/− mice that were WT or deficient in Fgr or Lyn were placed on a HFD at 6 wk of age for a total of 6 wk. Total number of individual plaques (A) or average plaque size (B) in the descending aorta was analysed (n = 10‐12 per group). *P < .05, ApoE ^−/− Fgr ^−/− and ApoE ^−/− Lyn ^−/− mice compared to ApoE ^−/− using one‐way ANOVA followed by a Dunnett (A) post‐test