Table 2.
The Box-Behnken (three-factor) design.
| Parameter/Conditions | Levels |
|---|---|
| Extraction temperature (°C) | 30, 50, 70 |
| Extraction time (min) | 15, 30, 45 |
| Sample volume (mL) in 20 mL vial | 7, 10, 13 |
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