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. 2018 Aug 6;7(8):202. doi: 10.3390/jcm7080202

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Generalized additive model (GAM) plot for the probability of (A) 90-day mortality, and (B) 90-day composite outcome against serum cFGF-23 levels at initiation of dialysis. Note: The GAM plot was incorporated with the subject-specific (longitudinal) random effects expressed as the logarithm of the odds (logit). The probability of outcome events was constructed with cFGF-23 levels averaging zero over the range of the data, i.e., cFGF-23 = 2050 ng/mL. All the relevant covariates, including characteristics, comorbidities, laboratory data, at intensive care unit (ICU) admission, etiology of acute kidney injury (AKI), indication for dialysis, dialysis modality, SOFA score, and plasma cFGF-23 at dialysis, and some of their interactions, such as interventions listed in Table 1, were put on a selected variable list to predict the outcome of interest.

Generalized additive model (GAM) plot for the probability of (A) 90-day mortality, and (B) 90-day composite outcome against serum cFGF-23 levels at initiation of dialysis. Note: The GAM plot was incorporated with the subject-specific (longitudinal) random effects expressed as the logarithm of the odds (logit). The probability of outcome events was constructed with cFGF-23 levels averaging zero over the range of the data, i.e., cFGF-23 = 2050 ng/mL. All the relevant covariates, including characteristics, comorbidities, laboratory data, at intensive care unit (ICU) admission, etiology of acute kidney injury (AKI), indication for dialysis, dialysis modality, SOFA score, and plasma cFGF-23 at dialysis, and some of their interactions, such as interventions listed in Table 1, were put on a selected variable list to predict the outcome of interest.