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. 2018 Aug 27;25:64. doi: 10.1186/s12929-018-0467-8

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Comparisons of B cell subsets during acute DENV infections. High level of ASCs was observed in dengue infected patients. Significantly lower frequencies of naïve and resting memory B cells were observed in patients when compare with healthy individuals (*p < 0.05, by Mann-Whitney U test). Significantly higher frequencies of plasmablasts/plasma cells or ASCs were observed in patients when compare with healthy individuals (***p ≤ 0.0005, by Mann-Whitney U test), whereas activated memory and tissue memory B cells were not significantly different when compare between patients with dengue and healthy individuals