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. Author manuscript; available in PMC: 2018 Aug 28.
Published in final edited form as: Pediatr Crit Care Med. 2017 Jun;18(6):e235–e244. doi: 10.1097/PCC.0000000000001183

Figure 3. Association of biomarkers from the first day of AKI attainment with AKI duration at least 48 hours.

Figure 3.

Boxplots of biomarker concentrations (y-axis) measured on the first PICU day the patient fulfilled criteria for AKI, in subjects with AKI duration (fulfilling criteria for AKI) less than vs. greater than or equal to 48 hours (indicated on x-axis). Within graph statistics shown are the p-value for biomarker concentration differences between the two groups (Mann-Whitney U test) and the area under the receiver operating characteristic curve for each biomarker to predict AKI duration at least 48 hours (with lower and upper 95% confidence interval). A) AKI defined using serum creatinine criteria. B) AKI defined using both serum creatinine or urine output criteria. Abbreviations: NGAL: neutrophil gelatinase associated lipocalin; IL-18: interleukin-18; LFABP: liver fatty acid binding protein; AUC: area under the curve; AKISCr: acute kidney injury defined using serum creatinine criteria; AKISCr+UO: acute kidney injury defined using serum creatinine criteria or urine output criteria.