Table 2.
Significant (LOD ≥4.3) linkage for colitis-related phenotypes detected by genome scans for main effects
Marker location | D3Mit348 61.8 cM | D12Nds2 59 cM | D17Nds3*/ D17Mit34† 19.06/18.8 cM |
---|---|---|---|
Spleen/body weight ratio | 15.9 | 5.9* | |
Mesenteric lymph node/body weight ratio | 7.4 | ||
Diarrhea | 18.1 | ||
sIgA (ng/ml) | 6.6 | 4.3 | |
Percentage of IgM+ B cells | 7.1 | ||
Percentage of CD8+ T cells | 6.1† |
Peak LOD score at D17Nds3.
Peak LOD score at D17Mit34.