Fig. 1.

Casz1 is a nuclear protein in photoreceptors. (A) Airyscan confocal images of mature rod and cone photoreceptors distinguished by staining for the cone photopigment S-opsin. (B) Airyscan confocal images of rods and cones costained for Casz1 or Otx2. (Scale bars: A, 5 μm; B, 2 μm.) (C) Magnified (5,000×) view of a rod photoreceptor shown in B. (D and E) Schematic of cone (conventional) (D) and rod (inverted) (E) nuclear organization. IS, inner segments; PRL, photoreceptor layer. (Scale bars: A, 5 μm; B, 2 μm.)