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. 2018 Aug 7;9(61):31904–31914. doi: 10.18632/oncotarget.25881

Figure 3. Influence of anticoagulant and blood preservation on quality of cfDNA from a patient with NSCLC harboring EGFR mutation.

Figure 3

cfDNA size distributions (A) in samples stored at 4° C or RT were compared in blood collected into sodium citrate tubes. Area under mutation peak (AUM) of L858R was examined with MBP-QP (B). Arrows indicate mutation peaks. AUM for L858R (indicated as M) was defined as the integral under the curve between 56° C and 68° C and was calculated by the i-densy AreaAna® software.