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. 2018 Aug 7;9(61):31904–31914. doi: 10.18632/oncotarget.25881

Figure 6. Influence of long-term storage of cfDNA on mutation detection.

Figure 6

The definition of AUM (indicated as M) is shown (A) The correlation between percentage reduction of T790M AUM after 7 years and the initial value of AUM (step (i) in Figure 5) was analyzed (B) The percentage reduction was calculated as [T790M AUM at initial examination (i) - T790M AUM after 7 years (ii)]/[T790M AUM at initial examination (i)]. Samples were divided into two groups on the basis of whether percentage reduction of T790M AUM after storage for 7 years was above or below the cut-off value 96.3 determined as the level that corresponded with 50% reduction according to the regression line (C) Freidman’s test was used for analysis.