Table 2.
Hemoglobin, other hemogram parameters and iron status parameters at baseline, at the end of the study and the corresponding absolute change
| Variable | Baseline | End of study | Absolute change | p-value | |||
|---|---|---|---|---|---|---|---|
| Hemoglobin (g/dL) | |||||||
| Mean (SD) | 10.3 | (0.6) | 11.2 | (1.6) | 0.9 | (1.3) | 0.001 |
| Serum iron (mg/mL) | |||||||
| Mean (SD) | 42.3 | (13.9) | 59.6 | (26.9) | 17.4 | (26.6) | 0.001 |
| Ferritin (ng/mL) | |||||||
| Mean (SD) | 230.3 | (248.1) | 877.0 | (601.2) | 646.7 | (455.7) | <0.001 |
| Transferrin (mg/mL) | |||||||
| Mean (SD) | 244.3 | (66.0) | 205.7 | (61.8) | −38.5 | (39.2) | <0.001 |
| Iron binding capacity (µg/dL) | |||||||
| Mean (SD) | 339.7 | (75.6) | 301.1 | (89.2) | −38.6 | (62.8) | 0.002 |
| TSAT (%) | |||||||
| Mean (SD) | 13.0 | (4.3) | 19.7 | (6.7) | 6.7 | (6.9) | <0.001 |
| MCV (fL) | |||||||
| Mean (SD) | 87.0 | (7.7) | 92.5 | (8.9) | 5.4 | (5.4) | <0.001 |
| MCH (pg) | |||||||
| Mean (SD) | 28.4 | (3.0) | 30.5 | (3.3) | 2.1 | (2.3) | <0.001 |
| MCHC (g/dL) | |||||||
| Mean (SD) | 32.5 | (1.2) | 33.0 | (1.1) | 0.5 | (1.3) | 0.059 |
| RDW (%) | |||||||
| Mean (SD) | 16.8 | (3.0) | 17.0 | (3.3) | 0.2 | (3.7) | 0.800 |
Abbreviations: MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red cell distribution width; TSAT, transferrin saturation.