. 2018 Aug 10;9(62):31985–31998. doi: 10.18632/oncotarget.25868

Table 1. Concentration of metabolites about glutathione metabolic pathways in USC cells.

Compound name	Concentration (pmol/10⁶ cells)
Compound name	USPC-1(Control)		USPC-1(Paclitaxel)		PTX-1(Control)		PTX-1(Paclitaxel)		USPC-1(Paclitaxel) vs USPC-1(Control)		PTX-1(Paclitaxel) vs PTX-1(Control)		PTX-1(Control) vs USPC-1(Control)		PTX-1(Paclitaxel) vs USPC-1(Paclitaxel)
	Mean	S.D.	Mean	S.D.	Mean	S.D.	Mean	S.D.	Ratio	P value	Ratio	P value	Ratio	P value	Ratio	P value
Folic acids	8.5	4.5	13	5.2	13	3.8	7.1	3.3	1.5	0.313	0.5	0.113	1.5	0.261	0.5	0.178
ADP	716	159	1,319	98	1,118	125	1,364	89	1.8	0.009^*	1.2	0.056	1.6	0.029^*	1.0	0.588
ATP	11,072	5,718	15,846	651	10,294	1,417	9,452	631	1.4	0.284	0.9	0.422	0.9	0.838	0.6	2.6E-04^*
Gly	11,954	4,697	16,374	245	16,379	1,012	15,489	914	1.4	0.244	0.9	0.322	1.4	0.241	0.9	0.231
Cys	436	482	519	251	1,796	262	1,950	304	1.2	0.851	1.1	0.545	4.1	0.112	3.8	0.004^*
Glu	64,248	16,387	83,494	2,271	75,376	3,081	65,793	4,357	1.3	0.177	0.9	0.041^*	1.2	0.360	0.8	0.008^*
Glutathione (GSSG)	1,679	402	2,208	239	2,158	352	1,480	123	1.3	0.138	0.7	0.066	1.3	0.197	0.7	0.019^*
Glutathione (GSH)	13,828	5,374	20,770	138	21,282	1,894	19,231	760	1.5	0.155	0.9	0.193	1.5	0.126	0.9	0.068
NADPH/NADP+	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.	N.A.

S.D.; standard deviation, ADP; adenosine diphosphate, ATP; adenosine triphosphate, NADPH; reduced nicotinamide adenine dinucleotide phosphate, NADP; nicotinamide adenine dinucleotide phosphate, ^*P < 0.05, N.A.; not available