Table 1.
Summary of discussion
Risk | ||||
Attempted ethical responses to the risk | Affecting active arm participants | Affecting placebo arm participants | Affecting sexual partners | Affecting fetuses |
Mitigation risk for participants | ✓ | ✓ | – | – |
Mitigating risk for nonparticipants | ? | ? | ✓ | ✓ |
Special selection criteria | ✓ | ✓ | ✓ | ✓ |
Informed consent | ✓ | ✓ | ? | ? |
Community engagement | ? | ? | – | ? |
Enhanced benefits | ✓ | ✓ | – | ? |
Social value | ✓ | ✓ | ✓ | ✓ |
The table lists attempted ethical responses to risks from remission studies and categorizes how relevant each response is to the risks to various populations.