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. Author manuscript; available in PMC: 2019 Aug 10.
Published in final edited form as: Environ Mol Mutagen. 2018 Aug 10;59(7):576–585. doi: 10.1002/em.22202

Figure 1.

Figure 1

Multivariate data analysis at D1. Panels A and B: Multidimensional scaling plot (MDS) for basal levels (A) and post irradiation at day 1 (B). Blue indicates WT, red Atm+/−, and black Atm−/−. Both MDS plots were constructed through Random Forests of the top 100 ranked ions. These same ions were used to construct heatmaps, with darker colors indicating higher normalized abundance per sample. Panel C: Volcano plot of basal levels and responses to semi-lethal doses, following removal of basal genotypic differences. Statistically significant ions (FDR < 0.1, Mann-Whitney U test) are highlighted in red.