TABLE 3.
Percent Change in Secondary Outcome Variables Across Intervention
| Probiotic (n=8) | Placebo (n=11) | P-valuea | |
|---|---|---|---|
| Change in Body Composition and Adiposity | M (SE) | M (SE) | |
| BMI (kg/m2) | 0.6 (0.2) | −0.07 (0.3) | 0.06 |
| Waist Circumference | 3.6 (1.7) | −0.3 (1.7) | 0.65 |
| Total Fat Mass (kg) | 2.1 (5.7) | −0.9 (0.6) | <0.01 |
| Total Lean Mass (kg) | −0.7 (0.7) | 1.3 (0.6) | 0.12 |
| Total Adiposity (%) | 1.7 (0.6) | −1.3 (0.5) | <0.01 |
| Trunk Fat Mass (kg) | 2.3 (0.8) | −0.2 (0.4) | <0.01 |
| Trunk Lean Mass (kg) | −0.1 (0.8) | 1.3 (0.5) | 0.14 |
| Trunk Adiposity (%) | 3.3 (0.7) | −1.8 (0.8) | <0.01 |
| VAT (liters) | 0.003 (0.4) | 0.07 (0.05) | 0.22 |
| SAT (liters) | 0.3 (0.4) | 0.04 (0.2) | 0.68 |
| Change in Liver Condition | |||
| Liver Adiposity (%) | 0.004 (0.4) | −0.8 (1.3) | 1.0 |
| Liver Fibrosis by MRE (kPa) | 0.3 (0.4) | 0.04 (1.2) | 0.46 |
| Change in Macronutrient Intake | |||
| Total Caloric Intake | 212.3 (296.0) | 108.7 (190.3) | 0.33 |
| Total Carbohydrates (%) | −0.2 (2.3) | 2.3 (3.7) | 0.79 |
| Total Sugar (%) | −2.4 (2.6) | −0.5 (2.2) | 0.42 |
| Added Sugar (%) | 1.4 (1.8) | 2.2 (2.2) | 0.66 |
| Total Fat (%) | 0.8 (1.8) | 0.36 (2.4) | 0.93 |
| Total Protein (%) | −0.6 (1.9) | −2.6 (2.4) | 0.66 |
Data are unadjusted percent change scores (relative to baseline), M (SE). P-value reflects the time by treatment interaction obtained from a linear mixed model controlling for baseline BMI.
VAT, visceral adipose tissue; SAT subcutaneous adipose tissue.