Table 1.
Nanogel formulations | Loading efficiency(%) | Loading content(%) | DLS diameter(nm) | PI | Zeta potential (mV) |
---|---|---|---|---|---|
Without drug | – | – | 233 | 0.06 | −25 ± 4.0 |
With SAHA | 45.2 ± 1.8 | 4.5 ± 0.2 | 228 | 0.2 | −10 ± 1.0 |
With DOX | 68.5 ± 8.5 | 6.8 ± 0.9 | 293 | 0.139 | −18 ± 0.3 |
With DAC | 79.9 ± 5.3 | 6.4 ± 0.4 | 244 | 0.11 | −19 ± 1.0 |
Data as mean ± s.e.m; n = 2 for DOX and SAHA; n = 4 for DAC. DLS, dynamic light scattering, PI, polydispersity index.