Figure 2.

Simulation results for testing the changes in the slope between pre- and post-transfusion using the proposed slope test and the standard slope test based on linear regression modeling of the rSO₂ measurements. (a) We compared type I error rate at various alpha levels when there was no difference in the rSO₂ slope between pre- and post-transfusion periods. The proposed test had type I errors that were closer to the nominal levels. (b) We compared the power of the tests for detecting the differences in rSO₂ slopes between pre- and post-transfusion period. The proposed test demonstrated higher power as compared with the standard slope test.