Table 4.
The average rSO2 level in pre- to post-transfusion periods based on the sample mean method and the proposed MAUC method for infants from the Emory NIRS study.
| The sample mean method |
The proposed MAUC method |
|||||||
|---|---|---|---|---|---|---|---|---|
| Subjecta | Pre-tran. (SE) |
Post-tran. (SE) |
Pre- to post- change |
p-Valueb | Pre-tran (SE) |
Post-tran. (SE) |
Pre- to post- change |
p-Valuec |
| A1 | 15.69 (0.64) | 52.44 (1.18) | 3.68 | <0.001 | 8.86 (0.93) | 52.18 (2.07) | 43.32 | <0.001 |
| A2 | 15.75 (0.63) | 27.66 (1.00) | 11.90 | <0.001 | 9.38 (0.86) | 25.46 (1.04) | 16.08 | <0.001 |
| B1 | 17.11 (0.76) | 16.04 (0.67) | −1.07 | 0.021 | 11.97 (1.17) | 8.98 (0.55) | −2.99 | <0.001 |
| B2 | 23.79 (1.06) | 42.13 (0.69) | 18.34 | <0.001 | 21.46 (1.60) | 41.02 (0.46) | 20.56 | <0.001 |
| C1 | 15.56 (0.56) | 17.08 (0.48) | 1.53 | <0.001 | 8.55 (0.75) | 11.65 (0.45) | 3.09 | <0.001 |
| C2 | 40.84 (1.01) | 49.08 (0.75) | 8.25 | <0.001 | 40.66 (1.19) | 49.11 (0.55) | 8.45 | <0.001 |
| D | 46.17 (1.03) | 35.32 (0.84) | −10.85 | <0.001 | 46.03 (1.63) | 34.63 (0.91) | −11.40 | <0.001 |
| E | 16.07 (0.59) | 22.99 (0.74) | 6.93 | <0.001 | 9.61 (1.26) | 20.22 (0.88) | 10.61 | <0.001 |
| F1 | 44.30 (0.86) | 44.16 (1.11) | −0.14 | 0.838 | 44.38 (1.06) | 43.20 (1.50) | −1.18 | 0.005 |
| F2 | 36.65 (1.05) | 49.38 (0.65) | 12.73 | <0.001 | 36.64 (0.88) | 49.40 (0.49) | 12.76 | <0.001 |
| G | 17.64 (0.77) | 19.80 (0.74) | 2.16 | <0.001 | 12.30 (1.07) | 15.43 (0.62) | 3.12 | <0.001 |
| H | 62.04 (1.85) | 50.58 (0.97) | −11.46 | <0.001 | 61.81 (3.27) | 50.45 (0.88) | −11.36 | <0.001 |
| I | 42.93 (0.94) | 51.55 (0.78) | 8.62 | <0.001 | 42.91 (0.93) | 51.47 (0.75) | 8.56 | <0.001 |
| J | 15.25 (0.39) | 29.84 (1.03) | 14.60 | <0.001 | 7.73 (0.55) | 27.87 (1.13) | 20.14 | <0.001 |
| K | 46.32 (1.65) | 56.25 (0.78) | 9.93 | <0.001 | 46.23 (2.61) | 55.96 (0.63) | 9.73 | <0.001 |
| L | 26.59 (1.09) | 32.30 (0.84) | 5.71 | <0.001 | 25.90 (1.36) | 31.77 (0.71) | 5.87 | <0.001 |
| M | 64.55 (1.37) | 18.92 (0.82) | −45.63 | <0.001 | 64.29 (2.06) | 13.82 (0.89) | −50.47 | <0.001 |
| N | 45.36 (0.93) | 43.76 (0.67) | −1.59 | <0.001 | 45.16 (0.70) | 43.64 (0.44) | −1.52 | <0.001 |
a
Different letters in the Subject list corresponding to different infants. For an infant who received multiple transfusions, a numeric value is added after a subject’s letter ID to denote different transfusions (e.g. A1 and A2 corresponding to NIRS data from the first and second transfusion from subject A).
b
The p-value of the pre- to post-transfusion change was derived from the t-test.
c
The p-value of the pre- to post-transfusion change was derived from the MI nested permutation test.