Table 5.
Pre- to post-transfusion changes in the rSO2 temporal trajectory based on the naïve slope estimate and the proposed slope estimate.
| Subjecta | The naïve slope method |
The proposed slope method |
||||||
|---|---|---|---|---|---|---|---|---|
| Pre-tran. (SE) |
Post-tran. (SE) |
Pre- to post- change |
p-Valueb |
Pre-tran. (SE) |
Post-tran. (SE) |
Pre- to post-change |
p-Valuec |
|
| A1 | −0.549 (0.298) | 0.849 (0.035) | 1.398 | 0.269 | −0.419 (0.813) | 0.857 (0.035) | 1.276 | <0.001 |
| A2 | 0.210 (0.167) | −0.073 (0.040) | −0.283 | 0.570 | 0.333 (0.408) | −0.068 (0.045) | −0.401 | <0.001 |
| B1 | 0.357 (0.718) | 0.061 (0.019) | −0.296 | 0.641 | 0.656 (1.496) | 0.082 (0.023) | −0.574 | 0.684 |
| B2 | −0.923 (0.415) | −0.026 (0.020) | 0.897 | 0.000 | −1.486 (0.640) | −0.038 (0.020) | 1.448 | <0.001 |
| C1 | −0.190 (0.196) | −0.051 (0.013) | 0.139 | 0.466 | −0.447 (0.400) | −0.106 (0.019) | 0.341 | 0.004 |
| C2 | 0.377 (0.397) | −0.002 (0.018) | −0.379 | 0.038 | 0.349 (0.419) | −0.017 (0.023) | −0.366 | <0.001 |
| D | −3.207 (0.278) | −0.166 (0.039) | 3.041 | 0.000 | −3.129 (0.272) | −0.196 (0.034) | 2.933 | <0.001 |
| E | −2.054 (0.853) | 0.025 (0.028) | 2.079 | 0.317 | −2.930 (2.475) | 0.020 (0.040) | 2.951 | <0.001 |
| F1 | 0.731 (0.327) | −0.130 (0.072) | −0.861 | 0.012 | 0.823 (0.403) | −0.142 (0.069) | −0.965 | <0.001 |
| F2 | −0.101 (0.593) | 0.057 (0.022) | 0.158 | 0.736 | −0.051 (0.621) | 0.055 (0.022) | 0.106 | 0.622 |
| G | 0.656 (0.312) | −0.076 (0.019) | −0.732 | 0.000 | 0.882 (0.448) | −0.111 (0.028) | −0.992 | <0.001 |
| H | −3.848 (0.567) | 0.030 (0.035) | 3.878 | 0.000 | −3.717 (0.660) | 0.015 (0.036) | 3.732 | <0.001 |
| I | 0.631 (0.238) | −0.104 (0.030) | −0.735 | 0.000 | 0.671 (0.262) | −0.097 (0.030) | −0.768 | <0.001 |
| J | −0.100 (0.104) | −0.136 (0.035) | −0.036 | 0.946 | −0.141 (0.272) | −0.165 (0.045) | −0.024 | 0.218 |
| K | −33.429 (4.16) | 0.037 (0.032) | 33.466 | 0.000 | −33.426 (3.99) | 0.029 (0.024) | 33.454 | <0.001 |
| L | −3.267 (0.270) | 0.153 (0.019) | 3.420 | 0.000 | −3.663 (0.320) | 0.146 (0.028) | 3.810 | <0.001 |
| M | −8.247 (4.272) | 0.158 (0.022) | 8.405 | 0.011 | −7.790 (4.381) | 0.240 (0.030) | 8.030 | <0.001 |
| N | 1.933 (0.430) | −0.024 (0.024) | −1.957 | 0.000 | 1.843 (0.395) | −0.033 (0.025) | −1.876 | <0.001 |
Note: The scale of the slope estimate and its SE is on 10−3.
a
Different letters in the Subject list corresponding to different infants. For an infant who received multiple transfusions, a numeric value is added after a subject’s letter ID to denote different transfusions.
b
The p-value of the pre- to post-transfusion change was derived from t-test.
c
The p-value of the pre- to post-transfusion change was derived from the MI nested permutation test.