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. 2018 Aug 28;9(9):858. doi: 10.1038/s41419-018-0909-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a, b The protein expression of CTSB, LAMP2 and p62 in mouse chondrocytes treated as above. c The protein expression of LC3 in mouse chondrocytes treated as above. d Immunofluorescence double-labeled staining for co-localization of LC3 with LAMP1 in mouse chondrocytes treated as above (Green: LC3, red: LAMP1, bar: 10 μm). d, e The protein expression of LC3, p62, LAMP2 and CTSB in mouse chondrocytes treated as above. f, h The Lysotracker staining in mouse chondrocytes treated as above (bar: 20 μm). g The quantitation of the percentage of co-location of LC3/LAMP1 was detected by image J. All data represent mean ± S.D. (n = 5). **P < 0.01