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. 2018 Aug 28;8:12961. doi: 10.1038/s41598-018-31005-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relationship between the presence of neutralizing antibodies to the human RV strain Wa (P[8]) and the FUT2 genotype in French healthy young adults. Presence of neutralizing antibodies against the RV strain Wa (P[8]) was determined in sera from 76 healthy individuals by serum virus neutralization assay. The distribution of each genotype was as follows: 28 homozygous secretors (SE/SE); 29 heterozygous secretors (SE/se) and 19 non-secretors (se/se). Titers were defined as the dilution of serum leading to a 50% inhibition of infection as compared to the positive control. Two groups of individuals were then defined: those for whom a titer was obtained and those for whom no titer was obtained. Chi-square test for trend was used to compare distributions (p < 0.02).