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. 2018 Aug 28;8:12971. doi: 10.1038/s41598-018-30827-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The global network metrics of the binary network. For the full range of network costs (0.03–0.40) of the binary network, no significant differences were found in the global network metrics among the PDM_MENS, CON_MENS, PDM_POV, and CON_POV by conducting linear mixed models. C_p, clustering coefficient; L_p, characteristic path length; CON_MENS, menstrual phase of the control group; CON_POV, periovulatory phase of the control group; PDM_MENS, menstrual phase of the primary dysmenorrhea group; PDM_POV, periovulatory phase of the primary dysmenorrhea group.