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. 2018 Aug 29;7:57. doi: 10.1038/s41377-018-0057-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a The mrO₂ calculated from the drO₂ difference of the arteriole and venule of a SKH1-Elite hairless albino mouse ear during wound healing on day 0 (no wound/control), day 1 (wound made), day 7, day 14, day 23, day 26, day 33, and day 36 post biopsy punch. b A comparison of ΔD calculated from the dermal skin of a wound during the healing process. The histograms show the results averaged over five or six independent wounds. All statistical values are compared with the values of day 0. For day 0, day 7, and day 27, n = 5; for day 1, day 14, day 23, day 33, and day 36, n = 6.The depth range to calculate ΔD was 90–200 µm from the skin surface. Error bar = SEM. *p < 0.05 (the p values of day 7–day 36 are 0.055, 0.038, 0.023, 0.040, 0.038, and 0.037, in order)