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. 2018 Aug 28;9(9):852. doi: 10.1038/s41419-018-0926-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a RT-PCR was conducted in HepG2 cells treated with different concentrations of sorafenib for 24 h. b Western blot experiments were performed in HepG2 cells treated with different concentrations of sorafenib for 24 h. c Cell supernatant was collected to perform the IL6 ELISA assay. d After incubated with 5 μM sorafenib for 24 h, cells were stained with SA-β-gal. *p < 0.05; **p < 0.01; ***p < 0.001, compared with Control. The scale bars represent 25 μm. All immunoblots indicate molecular size markers in kDa