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. 2018 Aug 28;9(9):851. doi: 10.1038/s41419-018-0937-7

Fig. 5. The functions of DSCR8 is mediated by miR-485-5p.

Fig. 5

miR-485-5p mimics suppressed, whereas miR-485-5p inhibitors promoted HCC cells' proliferation (a–c) and cell cycle (d). Meanwhile, miR-485-5p mimics induced, whereas miR-485-5p inhibitors inhibited HCC cells' apoptosis (e). miR-485-5p mimics partially offset the promotion effects of DSCR8 on Hep 3B cells' proliferation (a–c) and cell cycle (d) while reversed the inhibitory effects of DSCR8 on cells' apoptosis (e). miR-485-5p inhibitors reversed the inhibitory effects of sh-DSCR8 on Huh7 cells' proliferation (a–c) and cell cycle (d) while receded the promotion effects of sh-DSCR8 on cells' apoptosis (e). n = three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001