Table 2.
Correlation between miR-485-5p expression and the clinicopathologic characteristics in HCC
| Characteristics | Cases (n = 75) | Number of patients | P | ||
|---|---|---|---|---|---|
| miR-485-5plow (n = 38) | miR-485-5phigh (n = 37) | ||||
| Age (years) | <50 | 24 | 11 | 13 | 0.566 |
| ≥50 | 51 | 27 | 24 | ||
| Gender | Male | 64 | 33 | 31 | 0.708 |
| Female | 11 | 5 | 6 | ||
| HBV | Absent | 13 | 8 | 5 | 0.389 |
| Present | 62 | 30 | 32 | ||
| Serum AFP level (ng/mL) | <400 | 18 | 8 | 10 | 0.545 |
| ≥400 | 57 | 30 | 27 | ||
| Tumor size (cm) | <5 | 34 | 22 | 12 | 0.027 |
| ≥5 | 41 | 16 | 25 | ||
| Number of tumor nodules | 1 | 62 | 30 | 32 | 0.389 |
| ≥2 | 13 | 8 | 5 | ||
| Cirrhosis | Absent | 20 | 7 | 13 | 0.102 |
| Present | 55 | 31 | 24 | ||
| Venous infiltration | Absent | 54 | 23 | 31 | 0.025 |
| Present | 21 | 15 | 6 | ||
| Edmondson–Steiner grading | I+II | 49 | 20 | 29 | 0.019 |
| III+IV | 26 | 18 | 8 | ||
| TNM stage | I+II | 56 | 26 | 30 | 0.208 |
| III+IV | 19 | 12 | 7 | ||
HCC hepatocellular carcinoma, HBV hepatitis B virus, AFP alpha-fetoprotein, TNM tumor–node–metastasis
The bold values means their P-values <0.05.