Skip to main content
. 2018 Aug 22;9:1959. doi: 10.3389/fmicb.2018.01959

FIGURE 4.

FIGURE 4

Production of alpiniamides A-B (m/z 326 [M-H2O+H]+) and alpiniamide C (m/z 308 [M-H2O+H]+) by Streptomyces sp. IB2014/011-12 and its mutant strain IB2014/011-12ΔalpA1 lacking alpA1 gene. LC-MS chromatogram RT 2–6 min out of an overall 9 min gradient run is shown. Black line – extract of wild type Streptomyces sp. IB2014/011-12 and red line – extract of mutant strain lacking part of alpA1 gene and its promoter. Strains were cultivated for 7 days in NL19 medium. The peaks for alpiniamides are highlighted. Alpiniamide D elutes under these conditions together with main alpiniamides A and B.