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Calcium oxalate (CaOx) induces macrophage-like morphology in 3 days. (A) Primary monocytes were exposed to 1.0, 2.0, or 3.0 mM CaOx, or 20 ng/ml M-CSF for 3 days. After day 3, cells were stained with HEMA 3 kit for macrophage morphology. (B). Primary human monocytes were exposed to 0.50 or 1.00 mM of CaOx, potassium oxalate (K2Ox), or zinc oxalate (ZnOx) and incubated for 6 days. Images are representative of n = 3 at 20× magnification.
