Figure 2.

Apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like (APOBEC) genetic alterations in cancer. cBioPortal website was used to search 11 APOBEC gene family members across broad types of cancer studied in The Cancer Genome Atlas (TCGA), and the frequency of APOBEC genetic alterations from high to low were plotted. Analyses include samples with both copy number alterations and mutations data. Color bars represent different types of alteration (green, APOBEC mutation; blue, APOBEC gene deletion; red, APOBCEC gene amplification; grey, APOBEC gene multiple alterations). Circles of different colors represent different types of cancer studied in TCGA. There are 43 different studies listed in this plot