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Population pharmacokinetic models developed for burn patients
| N | Pharmacokinetic model | Pharmacokinetic parameters | Covariates | Reference |
|---|---|---|---|---|
| 37 | Two‐compartment |
Cl = 4.7L/h; V1 = 68.4 L; V2 = 73 L; Q = 4.54 L/h |
CL = 4.7 × (Clcr/6.53); V1 = 68.4 × (WT/70) − 33.1 × BURN; V2 = 73 × (WT/70) |
84 |
Cl, clearance; Clcr, creatinine clearance; N, sample size; Q, Intercompartmental clearance; V1, volume of central compartment; V2, volume of peripheric compartment; WT, weight.
