TABLE 7.
Accuracy of FluoroType MTDR to detect specific mutations in katG identified by Genotype MTBDRplus and sequencing
| katG genotypea | No. of isolates for which the genotype was: |
% of isolates | ||||||
|---|---|---|---|---|---|---|---|---|
| Identified by Genotype MTBDRplus and sequencing | Correctly identified by FluoroType MTBDR | Incorrectly identified by FluoroType MTBDR |
||||||
| Indeterminate | False resistance | Incorrect mutation | Undifferentiated mutation | Only WT was recorded | ||||
| WT | 257 | 254 | 2 | 1 | 98.8 | |||
| S315T1 | 42 | 42 | 100.0 | |||||
| S315T2 | 14 | 11 | 1 | 2 | 78.6 | |||
| S315I | 1 | 0 | 1 | 0.0 | ||||
| Het/mixed | 8 | 4 | 3 | 1 | 50.0 | |||
| Total | 322 | 311 | 96.6 | |||||
a
Definitions of abbreviations: WT, wild type, Het/mixed, heteroresistance and/or mixed infection.