TABLE 8.
Accuracy of FluoroType MTDR to detect specific mutations in inhA promoter identified by Genotype MTBDRplus and sequencinga
| inhA promoter genotype | No. of isolates in which the genotype was: |
% of isolates | ||||||
|---|---|---|---|---|---|---|---|---|
| Identified by Genotype MTBDRplus and sequencing | Correctly identified by FluoroType MTBDR | Incorrectly identified by FluoroType MTBDR |
||||||
| Indeterminate | False resistance | Incorrect mutation | Undifferentiated mutation | Only WT was recorded | ||||
| WT | 211 | 207 | 3 | 1 | 98.1 | |||
| T−15C | 100 | 99 | 1 | 99.0 | ||||
| G−17T | 4 | 0 | 1 | 3 | 0.0 | |||
| T−8A | 1 | 1 | 100.0 | |||||
| T−8C | 1 | 1 | 100.0 | |||||
| Het/mixed | 5 | 3 | 1 | 1 | 60.0 | |||
| Total | 322 | 311 | 96.6 | |||||
a
Definitions of abbreviations: WT, wild type; Het/mixed, heteroresistance and/or mixed infection.