TABLE 2.

In vitro caspofungin susceptibility testing using CLSI microdilution method and MBT ASTRA for 58 isolates of C. albicans

C. albicans strainsa	MIC (μg/ml)
	CLSI microdilution methodb		MBT ASTRA, 6 h
	24 h	48 h
1	8	8	4
2	8	>8	4
3	2	4	4
4	4	8	4
5	?	4	4
6	?	2	2
7	?	2	2
8	?	2	4
9	>8	>8	4
10	>8	>8	4
11	>8	>8	4
12	0.5	4	4
13	1	4	4
14	>8	>8	4
15	>8	>8	4
16	4	4	4
17	2	4	4
18	2	4	4
19	4	4	4
20	4	4	4
21	8	8	4
22	4	4	4
23	0.06	0.06	≤0.25
24	0.06	0.06	≤0.25
25	0.06	0.125	≤0.5
26	0.125	0.25	≤0.125
27	0.06	0.06	≤1
28	0.06	0.125	≤0.5
29	0.06	0.06	≤0.125
30	0.125	0.5	≤0.25
31	0.25	0.25	≤0.5
32	0.25	0.25	≤0.5
33	0.25	0.25	≤0.5
34	0.25	0.25	≤0.25
35	0.25	0.5	≤0.25
36	0.125	0.5	≤0.25
37	0.25	0.5	≤0.5
38	0.25	0.5	≤0.25
39	0.125	0.25	≤1
40	0.125	0.25	≤0.5
41	0.125	0.25	≤0.5
42	0.125	0.25	≤0.5
43	0.06	0.06	≤0.5
44	0.125	0.06	≤0.25
45	NAc	0.5d	≤0.5
46	0.06	0.06	≤0.25
47	0.25	0.125	≤0.25
48	0.125	0.25	≤0.125
49	0.06	0.06	≤0.5
50	0.125	0.06	≤0.5
51	0.06	0.06	≤0.25
52	0.125	0.125	NA
53	0.125	0.25	NA
54	0.25	0.25	NA
55	0.06	0.125	NA
56	0.25	0.25	NA
57	0.125	0.25	NA
58	0.06	0.06	NA
ATCC 64548	0.125	0.125	≤1
ATCC 64550	0.25	0.25	≤1
ATCC 22019e	1	2
ATCC 6258e	1	1

^aStrains 1 to 22 are resistant, and strains 23 to 58 are susceptible.

^bThe evaluation was performed visually.

^cNA, not available.

^dThe evaluation was performed by use of a microplate reader after 48 h.

^eThese quality control strains were tested only by the CLSI microdilution method.