TABLE 2.
Predicted antibiotic susceptibility phenotypes from WGS by Genefinder, Mykrobe, and Typewriter
| Antibiotic | Susceptibility prediction for Genefinder, Mykrobe, and Typewriter (n)a |
Discordant across methods (n [%]) | |||||
|---|---|---|---|---|---|---|---|
| RRR | SSS | RRS | RSR | RSS | SRS | ||
| Ciprofloxacin | 304 | 1,072 | 0 | 2 | 0 | 1 | 3 (0.2) |
| Clindamycin | 338 | 1,024 | 7 | 0 | 0 | 10 | 17 (1.2) |
| Erythromycin | 354 | 1,011 | 6 | 0 | 0 | 8 | 14 (1.2) |
| Fusidic acid | 151 | 1,221 | 4 | 0 | 0 | 3 | 7 (0.5) |
| Gentamicin | 76 | 1,300 | 1 | 0 | 0 | 2 | 3 (0.2) |
| Methicillin | 393 | 984 | 2 | 0 | 0 | 0 | 2 (0.1) |
| Mupirocin | 15 | 1,362 | 0 | 0 | 2 | 0 | 2 (0.1) |
| Penicillin | 1,161 | 211 | 3 | 0 | 0 | 4 | 7 (0.5) |
| Rifampin | 23 | 1,354 | 0 | 1 | 0 | 1 | 2 (0.1) |
| Tetracycline | 121 | 1,249 | 4 | 0 | 0 | 5 | 9 (0.7) |
| Trimethoprim | 175 | 1,199 | 3 | 1 | 0 | 1 | 5 (0.4) |
| Vancomycin | 0 | 1,379 | 0 | 0 | 0 | 0 | 0 (0.0) |
| Total (% of 16,548) | 3,111 (18.8) | 13,366 (80.8) | 30 (0.2) | 4 (0.02) | 2 (0.01) | 35 (0.2) | 71 (0.4) |
a
n = 1,379. R, resistant; S, susceptible.