Table 2.

Differences in the TCR phenotype between nodal EBV‐negative and EBV‐positive CTL

	Nodal EBV‐negative CTL (n = 47) (n [%])	Nodal EBV‐positive CTL (n = 41) (n [%])	P
T‐cell type	39/47 (82)	33/41 (80)	.79
αβ T (TCR β positive)	23/47 (48)	18/41 (43)	.67
γδ T (TCR γ positive and/or δ positive)	4/47 (8)	5/41 (12)	.73
TCR‐silent	12/47 (25)	10/41 (24)	1.0
NK‐cell type	8/47 (17)	8/41 (19)	.79

CTL, cytotoxic molecule (CM)‐positive peripheral T‐cell lymphoma; EBV, Epstein‐Barr virus; NK, natural killer; TCR, T‐cell receptor.

Patients with T‐cell type showed positivity for TCR protein expression and/or TCRγ gene rearrangement. TCR‐silent cases were negative for TCRβ, γ, and δ expression but positive for clonal TCRγ gene rearrangement. Patients with NK‐cell type did not have any of the TCR protein expression or clonal TCRγ gene rearrangement. One case of nodal EBV‐negative CTL had TCRβ and γ double positive type.