Table 2. Data on baseline IGFBP3, ΔIGF - 1, ΔIGFBP - 3 and ΔHeight SDS according to group type. Group 1, responders to growth hormone, Group 2, responders to IGF - 1 but not to growth hormone, Group 3, non-responder to growth hormone nor IGF - 1a.
Groups | IGFBP - 3, Baseline, mg/L (SDS) | ΔIGF - 1, ng/ml (SDS) | ΔIGFBP - 3 | ΔHeight SDS |
---|---|---|---|---|
Group 1, Responder- rGH | 3.29 ± 0.86b ,(0.32 ± 1.18b) | 216.72 ± 119.3b, d ,( 4.34 ± 2.6b, d) | 1.02 ± 1.41 | 0.45 ± 0.31b |
Group 2, Responder- rIGF - 1 | 2.76 ± 1.02c, (-0.46 ± 1.40c) | 101.73 ± 69.8d ,(2.08 ± 1.48d) | 1.26 ± 1.06 | 0.42 ± 0.35c |
Group 3, Non-responder- rGH and rIGF - 1 | 1.72 ± 0.79b, c ,(-2.08 ± 1.36b , c) | 35 ± 26.2b, (1.52 ± 1.22b) | 0.63 ± 0.48 | 0.11 ± 0.15b, c |
Abbreviations: IGF-1,Insulin like growth factor 1; IGFBP-3, Insulin like growth factor binding protein 3; GH, Growth hormone; SDS, standard deviation score.
aValues are presented as mean ± SD.
bP < 0.05 between group 1 and group 3.
cP < 0.05 between group 2 and group 3.
dP < 0.05 between group 1 and group 2.