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. 2018 Aug 28;14:1744806918797032. doi: 10.1177/1744806918797032

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© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Miniature inhibitory postsynaptic currents (mIPSCs) in spinal dorsal horn neurons of normal and neuropathic SOD2-KO mice and their WT littermates. (a) Representative traces of mIPSCs in each group. The summary graphs of the mean frequency (b) and amplitude (c) of mIPSCs in each group. In the normal condition, the frequency of mIPSC did not differ between SOD2-KO and WT mice. mIPSC frequency decreased significantly by SNL and the decrease was not reversed by mT perfusion. Amplitudes of mIPSC were not different between groups. *p < 0.05 between normal vs. SNL by two-way analysis of variance followed by Holm–Sidak multiple comparison tests. WT: wild-type; SNL: spinal nerve ligation.