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. 2018 Aug 22;9:661. doi: 10.3389/fneur.2018.00661

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Copyright © 2018 Chiu, Lin, Tzang, Li, Lin, Das, Chen, Chen and Hsu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The choice of optic/imaging systems could affect resolution and sensitivity of anti-NMDAR detection. Clinical samples were tested with the IIFT kit, and their images taken by a conventional fluorescence microscope (left) and by an advanced imaging system from TissueGnostics GmbH (right) were compared. Top: images from a sample with a low anti-NMDAR titer (1:10). Middle: images from a sample with a high anti-NMDAR titer (1:320). Bottom: images from an anti-NMDAR-negative sample. Scale bars, 20 μm.