Table 1. Zebrafish anatomical structures showing a significant enrichment in expression of genes with a pectoral fin phenotype (FDR < 1%).
The “weight” algorithm of the topGO package was used to decorrelate the structure of the ontology.
| organId | organName | annotated | significant | expected | foldEnrichment | pValue | FDR |
|---|---|---|---|---|---|---|---|
| UBERON:0004357 | paired limb/fin
bud |
144 | 41 | 7.15 | 5.7 | 1.6E-22 | 1.4E-19 |
| UBERON:0000151 | pectoral fin | 420 | 70 | 20.85 | 3.4 | 1.0E-18 | 4.6E-16 |
| UBERON:2000040 | median fin
fold |
51 | 18 | 2.53 | 7.1 | 7.2E-12 | 2.1E-09 |
| UBERON:0003051 | ear vesicle | 304 | 41 | 15.09 | 2.7 | 3.1E-10 | 7.0E-08 |
| UBERON:0005729 | pectoral
appendage field |
16 | 10 | 0.79 | 12.7 | 4.0E-10 | 7.1E-08 |
| UBERON:0007390 | pectoral
appendage cartilage tissue |
17 | 9 | 0.84 | 10.7 | 2.4E-08 | 3.6E-06 |
| UBERON:0011610 | ceratohyal
cartilage |
29 | 11 | 1.44 | 7.6 | 4.8E-08 | 6.1E-06 |
| UBERON:0004376 | fin bone | 28 | 9 | 1.39 | 6.5 | 4.3E-06 | 4.8E-04 |
| UBERON:0003351 | pharyngeal
epithelium |
70 | 14 | 3.48 | 4.0 | 4.9E-06 | 4.8E-04 |
| UBERON:0002513 | endochondral
bone |
37 | 10 | 1.84 | 5.4 | 7.1E-06 | 6.3E-04 |
| UBERON:0008001 | irregular bone | 30 | 9 | 1.49 | 6.0 | 8.2E-06 | 6.6E-04 |
| UBERON:0008907 | dermal bone | 46 | 11 | 2.28 | 4.8 | 8.9E-06 | 6.6E-04 |
| UBERON:0002539 | pharyngeal
arch |
518 | 61 | 25.72 | 2.4 | 1.1E-05 | 7.1E-04 |
| UBERON:0000089 | hypoblast
(generic) |
85 | 15 | 4.22 | 3.6 | 1.1E-05 | 7.1E-04 |
| UBERON:0002541 | germ ring | 94 | 15 | 4.67 | 3.2 | 3.9E-05 | 2.3E-03 |
| UBERON:0001003 | skin
epidermis |
109 | 16 | 5.41 | 3.0 | 6.2E-05 | 3.5E-03 |
| UBERON:0004375 | bone of free
limb or fin |
23 | 7 | 1.14 | 6.1 | 8.0E-05 | 4.2E-03 |
| UBERON:0000165 | mouth | 97 | 21 | 4.82 | 4.4 | 1.0E-04 | 4.8E-03 |
| UBERON:0011152 | dorsal hyoid
arch skeleton |
24 | 7 | 1.19 | 5.9 | 1.1E-04 | 4.8E-03 |
| UBERON:0000925 | endoderm | 126 | 17 | 6.26 | 2.7 | 1.1E-04 | 4.8E-03 |
| UBERON:0003128 | cranium | 283 | 31 | 14.05 | 2.2 | 1.3E-04 | 5.5E-03 |
| UBERON:0010312 | immature eye | 447 | 41 | 22.19 | 1.8 | 1.9E-04 | 7.7E-03 |