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. 2018 Aug 22;12:571. doi: 10.3389/fnins.2018.00571

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Copyright © 2018 Elsen, Bedogni, Hodge, Bammler, MacDonald, Lindtner, Rubenstein and Hevner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histone acetylases (HATs) and deacetylases (HDACs). (A–G) Expression of indicated genes. Hat1 (A) and Kat7 (B) were RGP-specific. Interestingly, Hdac9 (E) and Hdac5 (G) showed complementary zonal expression in VZ/SVZ and IZ/CP, respectively. ISH: Genepaint (A–E,G) and Allen Institute (F). Scale bar: 100 μm. (H) Cell-type-specific gene expression and regulation. Tbr2, Tbr1, and Mir9-2 regulate a switch from Hdac9 in progenitors, to Hdac5 in PNs. (I) No HATs or HDACs exhibited regional expression gradients.