Table 4.
Survival outcome en bloc removal versus morcellation
| Reference | Number of patients | Recurrence | RFS (months) | Abdominopelvic recurrence | Died of disease | Survival outcome |
|---|---|---|---|---|---|---|
| Perri et al., 2009[37] | 21 en bloc 16 morcellation, power and hand/tumor injury |
Morcellation 9 (56%) | En bloc versus morcellation 8 (38%) versus 10 (62%) | |||
| Park et al., 2011[38] | 31 en bloc 25 morcellation, power and hand |
En bloc versus morcellation 7 (22%) versus 13 (52%); P=0.02* | En bloc versus morcellation 10 (3-68) versus 9 (1-102) | En bloc versus morcellation 12.9 versus 44%; P=0.032 | En bloc versus morcellation 6 (19.4%) versus 11 (44%); P=0.04* | En bloc versus morcellation 5 years DFS: 65% versus 40%; P=0.04* 5 years OS: 73% versus 46%; P=0.04* |
| George et al., 2014[39] | 39 en bloc 19 morcellation, power and hand |
En bloc versus morcellation 20 (51%) versus 14 (73.7%) | En bloc versus morcellation 39.6 versus 10.8; P=0.02* | En bloc versus morcellation 4 (20%) versus 85.7; P=0.01* RR 3.1 (95% CI 1.5-6.5) | En bloc versus morcellation 13 (33.3%) versus 8 (42.1%) | En bloc versus morcellation 3 years OS: 73% versus 64%; P=0.21 Median OS: Not reach versus 48 months |
| Bogani et al., 2015[40] | 127 en bloc 75 morcellation, power and hand |
En bloc versus morcellation 39% versus 62%; P=0.007* | En bloc versus morcellation 9% versus 39%; P<0.01* OR 3.63 (95% CI 0.82–16.11) | En bloc versus morcellation 29% versus 48%; P=0.01* OR 2.4 (95% CI 1.2-4.8) | ||
| Gao et al., 2016[17] include ESS MMMT | 6 en bloc 11 morcellation, power and hand |
En bloc versus morcellation 37.9% versus 50%; P=0.36 | En bloc versus morcellation 90 versus 60 months | En bloc versus morcellation 5 (71%) versus 6 (66%); P=0.36 | En bloc versus morcellation 5 years RFS 43.5% versus 24% OS 43% (50 months) versus 37.8% (60 months) | |
| Lin et al., 2015[41] | 29 en bloc 14 morcellation, power and hand |
En bloc versus morcellation 48.3% versus 57.1%; P=0.83 | En bloc versus morcellation 2 (14.2%) versus 3 (37.5%); P=0.3 | En bloc versus morcellation 13 (44.8%) versus 7 (50%) | Morcellation group HR 2.16 (P=0.99) and 2.31 (P=0.84) | |
| Raine-Bennett et al., 2016[18] | 76 en bloc 35 morcellation, power and hand |
En bloc versus morcellation 34 (53%) versus 18 (62%) | En bloc versus morcellation 14 (41%) versus 13 (72%); P=0.03* | En bloc versus morcellation 40% versus 37%; P=0.75 | En bloc versus morcellation 5 years DFS: 54% versus 44%; P=0.27 OS: 64 versus 74%; P=0.89 |
*
P<0.05 - statistic significant. CI: Confidence interval, OR: Odds ratio, RR: Relative ratio, DFS: Disease-free survival, OS: Overall survival, HR: Hazard ratio, RFS: Recurrence-free survival