Fig. 1.

Percent of A/T/N misclassifications for the different biomarker combinations in (A) the whole sample, (B) cognitively healthy controls, (C) mild cognitive impairment and (D) dementia subjects. The percent of participants classified in different categories are shown for each biomarker combination when compared with classification with Aβ 1–42, p-tau, and t-tau. Percent of misclassifications are shown in green when one biomarker was changed, and in orange, when two biomarkers were changed. Abbreviations: Aβ, amyloid β; ADsig, Alzheimer’s disease cortical signature; aHV, adjusted hippocampal volume; FBP PET, [18F] florbetapir positron emission tomography; FDG PET, [18F] fluorodeoxyglucose positron emission tomography; p-tau, phosphorylated tau; t-tau, total tau.