Fig. 3.

Absolute correlation coefficient within and across amyloid, tau and neurodegeneration biomarkers along the AD continuum. (A) Significant correlations* between biomarkers in different pathophysiological categories along the AD clinical continuum; (B) Significant correlations* between biomarkers in the same pathophysiological category along the AD clinical continuum; *: a relevant correlation was defined by a correlation coefficient >0.3 in at least one clinical category of the AD continuum. The 0.3 threshold is marked with a red-dotted line. Abbreviations: AD, Alzheimer’s disease; Aβ, amyloid β; FDG, [18F] fluorodeoxyglucose; FBP, [18F] florbetapir.