. 2018 Jan 31;8(1):59–66. doi: 10.1016/j.ijpddr.2018.01.002

Table 2.

HDAC inhibitory effect of the compound 363 as compared to SAHA.

rHDAC	363 IC₅₀ μM	SAHA IC₅₀ μM	Fold
HDAC 1	0.257 ± 0.050	0.627 ± 0.039	2.43
HDAC 3	0.160 ± 0.052	0.170 ± 0.014	1.06
HDAC 6	0.045 ± 0.015	1.573 ± 0.800	34.9
HDAC 8	0.863 ± 0.045	0.230 ± 0.130	0.26