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. 2018 Mar 2;8(1):112–124. doi: 10.1016/j.ijpddr.2018.02.003

Table 1.

Experimental design.

Group Number of pregnant ewes Number of foetuses/lambs Inoculum (i.v.) Treatment (s.c.)
G1 8 14 Nc-Spain7
106 tachyzoites
BKI-1553, 1st dose: 35 mg/kg bodyweight; a week later, a 2nd dose at 10 mg/kg bodyweight
G2 5 7 PBS BKI-1553, 1st dose: 35 mg/kg bodyweight; a week later, a 2nd dose at 10 mg/kg bodyweight
G3 8 13 Nc-Spain7
106 tachyzoites
BKI-1553, 7 doses at 10 mg/kg bodyweight every other day
G4 5 9 PBS BKI-1553, 7 doses at 10 mg/kg bodyweight every other day
G5 8 13 Nc-Spain7
106 tachyzoites
None
G6 3 5 PBS None

i.v.: intravenous route.

s.c.: subcutaneous route.