Fig. 4.

HTS identifies compounds of NCC library that inhibit S. neurona growth. Screening data from two independent screens of NCC library. Open triangles indicate compounds with host-cell toxicity. The horizontal dotted line represents the 80% inhibition cut-off for selecting screening ‘hits’ (red) from non-inhibitory compounds (blue). Known inhibitory compound pyrimethamine included as positive control (green). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)